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Hypersensitivity to barbiturates or any part from the formulation; ; history of manifest or latent porphyriabutabarbital will minimize the extent or impact of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.butabarbital will lower the level or impact of diazepam intranasal by impacting hepatic/intestinal enz

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